Multi-attribute Process Intensification

Many processes rely on multiple CQAs. These CQAs often require conflicting set of process parameters for an optimal performance. For example, a set of process parameters that give the best process throughput (yield) in the manufacturing campaign of a chiral API is often not well suited for the best chiral selectivity (ee). It is important to measure all CQAs in parallel during process development in order to make an informed decision during process intensification following the guideline of QbD principles. Measuring multiple attributes from a flowed process won't have to be sample size, cost, or time limiting. We can help you utilize a unique recirculatory multi-attribute process intensification platform that will allow you to measure all CQAs by recirculating a single sample for a multiple time through a custom chromatographic network until all aspects of analysis are judged complete.

Please contact us to learn more about the multi-attribute process intensification platform.